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4-[1-[4-[2-(dimethylamino)ethoxy]phenyl]-2-phenylbut-1-enyl]phenol and 4-hydroxy-n-desmethyltamoxifen

4-[1-[4-[2-(dimethylamino)ethoxy]phenyl]-2-phenylbut-1-enyl]phenol has been researched along with 4-hydroxy-n-desmethyltamoxifen in 7 studies

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's7 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Curpan, RF; Jordan, VC; Lewis-Wambi, JS; Maximov, PY; Myers, CB1
Bourassa, P; Dubeau, S; Fauq, AH; Maharvi, GM; Tajmir-Riahi, HA; Thomas, TJ1
Cushman, M; Flockhart, DA; Liu, J; Lu, D; Lv, W1
Demizu, Y; Inoue, H; Kato, M; Kurihara, M; Naito, M; Okuhira, K; Shoda, T1
Curpan, RF; Fernandes, DJ; Jordan, VC; Maximov, PY; McDaniel, RE; Myers, CB1
Demizu, Y; Fujisato, T; Harada, R; Inoue, H; Kato, M; Kurihara, M; Naito, M; Okuhira, K; Shoda, T1
Capuzzi, SJ; Fisher, EG; García-Sastre, A; He, S; Li, H; Martínez-Romero, C; Muratov, EN; Qiu, X; Shinn, P; Sun, W; Tawa, G; Tropsha, A; Xu, M; Zheng, W; Zhu, W1

Other Studies

7 other study(ies) available for 4-[1-[4-[2-(dimethylamino)ethoxy]phenyl]-2-phenylbut-1-enyl]phenol and 4-hydroxy-n-desmethyltamoxifen

ArticleYear
Structure-function relationships of estrogenic triphenylethylenes related to endoxifen and 4-hydroxytamoxifen.
    Journal of medicinal chemistry, 2010, Apr-22, Volume: 53, Issue:8

    Topics: Binding Sites; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Crystallography, X-Ray; Estrogen Antagonists; Estrogens, Non-Steroidal; Ethylenes; Female; Humans; Models, Molecular; Receptors, Estrogen; Stereoisomerism; Structure-Activity Relationship; Tamoxifen

2010
Locating the binding sites of anticancer tamoxifen and its metabolites 4-hydroxytamoxifen and endoxifen on bovine serum albumin.
    European journal of medicinal chemistry, 2011, Volume: 46, Issue:9

    Topics: Antineoplastic Agents, Hormonal; Binding Sites; Circular Dichroism; Models, Molecular; Protein Structure, Secondary; Serum Albumin, Bovine; Spectrometry, Fluorescence; Spectroscopy, Fourier Transform Infrared; Tamoxifen

2011
Synthesis of mixed (E,Z)-, (E)-, and (Z)-norendoxifen with dual aromatase inhibitory and estrogen receptor modulatory activities.
    Journal of medicinal chemistry, 2013, Jun-13, Volume: 56, Issue:11

    Topics: Administration, Oral; Animals; Antineoplastic Agents; Aromatase Inhibitors; Biological Availability; Estrogen Receptor alpha; Estrogen Receptor beta; Estrogen Receptor Modulators; Humans; Mice; Mice, Inbred NOD; Mice, SCID; Models, Molecular; Protein Binding; Stereoisomerism; Structure-Activity Relationship; Tamoxifen

2013
Design and synthesis of tamoxifen derivatives as a selective estrogen receptor down-regulator.
    Bioorganic & medicinal chemistry letters, 2014, Jan-01, Volume: 24, Issue:1

    Topics: Dose-Response Relationship, Drug; Down-Regulation; Drug Design; Humans; MCF-7 Cells; Molecular Structure; Receptors, Estrogen; Structure-Activity Relationship; Tamoxifen

2014
Influence of the length and positioning of the antiestrogenic side chain of endoxifen and 4-hydroxytamoxifen on gene activation and growth of estrogen receptor positive cancer cells.
    Journal of medicinal chemistry, 2014, Jun-12, Volume: 57, Issue:11

    Topics: Animals; Cell Line; Cell Line, Tumor; Cell Proliferation; Cycloheptanes; Estrogen Receptor Modulators; Humans; Molecular Docking Simulation; Rats; Receptors, Estrogen; Stereoisomerism; Structure-Activity Relationship; Tamoxifen; Transcriptional Activation

2014
Synthesis and evaluation of tamoxifen derivatives with a long alkyl side chain as selective estrogen receptor down-regulators.
    Bioorganic & medicinal chemistry, 2015, Jul-01, Volume: 23, Issue:13

    Topics: Binding Sites; Blotting, Western; Down-Regulation; Estrogen Antagonists; Estrogen Receptor alpha; Gene Expression; Humans; Hydrophobic and Hydrophilic Interactions; MCF-7 Cells; Molecular Docking Simulation; Protein Binding; Protein Structure, Secondary; Structure-Activity Relationship; Tamoxifen

2015
Computer-Aided Discovery and Characterization of Novel Ebola Virus Inhibitors.
    Journal of medicinal chemistry, 2018, 04-26, Volume: 61, Issue:8

    Topics: Animals; Antiviral Agents; Chlorocebus aethiops; Drug Discovery; Drug Evaluation, Preclinical; Ebolavirus; HeLa Cells; Humans; Molecular Structure; Quantitative Structure-Activity Relationship; Small Molecule Libraries; Vero Cells; Virus Internalization

2018